Blood tests measure the IgG and IgE antibodies against an allergen. These antibodies can only be detected by blood fractionation (the process of separating blood into its various components), which is considered as both labour-intensive and expensive. In addition, since blood antibodies have a delayed immune response, food sensitivities cannot be accurately detected.
Skin prick tests are somewhat similar to blood tests as they also detect IgE antibodies against an allergen. However, the results are obtained faster. It is important to note that both blood and skin testing identify true allergies (anaphylactic responses) whereas DNA testing measures sensitivities and not just severe or life-threatening allergies.
DNA tests (saliva-based) measure IgA and IgM antibodies that are produced by the dog’s mucous membrane in response to allergens which they are sensitive to. Hence, these antibodies are measured in order to identify your dog’s sensitivities. Apart from the fact that saliva-based testing is painless, it is also accurate and affordable.